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The 7 Best Online Prescription Skincare Sites That’ll Save You a Trip to the Derm

There's a cure for that stubborn acne.
The 7 Best Online Prescription Skincare Sites That'll Save You a Trip to the Derm
Curology

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Did you know that different types of acne need different healing ingredients? What about the fact that over the counter retinol should be your first step, but once you’ve used one or two containers of product, it’s time to level up with stronger retinol you can only get from a derm? My friends! Welcome to the world of online prescription skincare, a magical place where you can send in photos of your skin ailments, get evaluated by a real life dermatologist and then get your “cure” shipped directly to your door—all for much less than the cost of going into an actual doctor’s office.

Best Online Prescription Skincare Sites at a Glance

Listen, doctors can complain all they want that online prescriptions are taking over their usual bread and butter, but IMO there’s absolutely no reason why me walking into a room and a doctor looking at my skin for four minutes should cost me nearly $300. Most insurance companies don’t even consider a yearly derm check to be necessary! But I digress… Nowadays, you can get just about any routine prescription prescribed online for a fraction of the cost.

If you’re looking for the best places to get prescription skincare for anything that’s troubling you, like acne, dark spots, or even newly appearing fine lines and wrinkles, you’ve come to the right place. Here are our picks for the best places to check out if you want to cure your skincare concerns and save some cash at the same time.

The 7 Best Online Prescription Skincare Companies For Retinol & More in 2025
Curology
Curology lets you upload photos of your skin for one of the 100 licensed dermatologists to review and then create a custom formula for you based on your needs. You can also choose from additional non-comedogenic add-ons for your skincare routine, like moisturizers, cleansers and more. Prices start at $30 for the custom formula each month (this goes up if you tack on additional products). If you don’t see results in three months, send it back for free!

Average cost: You can test out the service for free your first month; just pay the $4.95 shipping fee. Afterwards, prices range from $30-$60, depending on your treatment plan.
Insurance accepted: No
The 7 Best Online Prescription Skincare Companies For Retinol & More in 2025
Nurx
Nurx has prescription skincare, birth control, UTI meds and much more. It’s basically your one-stop shop for everything you need to survive as a woman without having to shell out hundreds of dollars hitting up all your different specialists. Whether you’re dealing with acne, aging, melasma, rosacea, or any other specific concerns, Nurx has a skincare formulation to prescribe. The services licensed medical providers will evaluate your skin history and prescribe a personalized treatment based on the severity of your issues.

Average cost: Nurx works with select insurance companies, so pricing may vary based on your provider plan. Most skincare formulations roughly cost $30 per month (billed $60 every two months).
Insurance accepted: Yes
The 7 Best Online Prescription Skincare Companies For Retinol & More in 2025
Hers
Hers offers a range of prescription skincare treatments that tackle wrinkles, acne, dark spots, and more. All you have to do is answer a survey to share information about your concerns, needs and skin type. From there, a Hers dermatologist will curate a selection of active ingredients for your formulation to remedy your issues.

Average cost: Most skincare treatments will cost around $20-$40 per month, with prices for additional Hers products (such as weight loss and hair loss treatments) sitting much higher. You can purchase bundle deals or opt into a subscription to save on costs.
Insurance accepted: No but HSA/FSA funds are accepted
Musely The Anti-Aging Cream
Musely.
Musely
Dark spots? Rosacea? Hair loss? Eye wrinkles? Musely can help with it all. It even takes it all a step further to offer more personalized treatments for ~down there~ as well as dark spot relief on places beyond the face, such as the body and neck.

Average cost: An online visit with a dermatologist costs $20 upfront. After your consult, prescribed solutions cost between $50 and $110. Your 60 day check-in to see how your treatment is working is free. Overall costs vary depending on whether you purchase a one-time treatment or opt into auto-refills.
Insurance accepted: No but HSA/FSA funds are accepted
The 7 Best Online Prescription Skincare Companies For Retinol & More in 2025
Ro
Not only can you get a personalized fertility testing kit sent directly to your door, but prescriptions for skincare, hair loss and sexual health with Ro. Your custom Rx skincare treatment could contain a handful of transformative ingredients, such as tretinoin, azelaic acid, tranexamic acid and more. Ro is also one of the most cost-effective online services on our list; you can get 25 percent off your first order.

Average cost: $43 for two months worth of custom Rx skincare treatment
Insurance accepted: No
The 7 Best Online Prescription Skincare Companies For Retinol & More in 2025
Wisp
Get emergency contraception, vaginal health prescriptions and skincare to boot at this one stop shop for women’s health. Simply fill out the quiz, connect with a Wisp professional and get your prescription sent to your local pharmacy for same-day pick-up or select free shipping to have your items sent straight to your door. Try the Wisp acne cream made with clindamycin and retin-A for powerful, prescription-only results.

Average cost: Costs vary based on product selection, but membership starts at $30 per month for a 3 or 12 month subscription
Insurance accepted: No but HSA/FSA funds are accepted
Agency Future Formula bottle with phone with the Agency app opened
Agency.
Agency
Agency lets you try out your customized formula for just the cost of shipping for 30 days. If some things are working while others aren’t, the derms on the team will reshape the formula until it’s exactly what your skin needs. There’s tons of options for building your perfect routine; craft your personal cleanser, SPF, eye cream and targeted serums.

Average cost: Costs vary based on product selection, but a 2-month supply of a customized Future Formula is $80. Prices can go lower if you opt for simpler formulations, like an SPF or cleanser.
Insurance accepted: No but HSA/FSA funds are accepted

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