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Looking to ward off unwarranted “you look tired” comments with a literal glow-up? Vitamin C is the answer. This potent antioxidant can brighten your complexion, fade dark spots, and boost collagen production, which helps combat signs of aging like fine lines, wrinkles, and elasticity. What’s more to love is that in serum form, vitamin C easily fits into your already-established daily routine, post-toner, and pre-moisturizer. However, with the recent influx of attention this hero ingredient has been getting, it takes a bit of homework to figure out which products are actually worth investing in.
The good news? You don’t have to spend time searching for one, as we dug into our beauty stashes and read thousands of reviews to recommend the best vitamin C serums. And for all of your frequently asked questions on how to use, pair, and pick vitamin C serums, we consulted board-certified dermatologists Dr. Brendan Camp of MDCS Dermatology and Dr. Marisa Garshick, Clinical Assistant Professor of Dermatology at Cornell – New York Presbyterian Medical Center.
Let’s take a quick science refresher to understand the benefits of using a vitamin C serum. Meet free radicals: unstable oxygen molecules—generated by exposure to external factors like environmental pollution and UV rays—that damage cellular structures like DNA, lipids, and proteins. This damage can cause the skin’s collagen to break down, contributing to aging features, such as sun spots, fine lines, and skin laxity. According to Dr. Camp, when applied topically, the antioxidant vitamin C minimizes and reverses these skin concerns, aiding your skin’s natural cell-repairing regeneration process by “neutralizing free oxygen radicals” and “encouraging collagen production.”
While you can use vitamin C serum in your nighttime routine, our experts say applying it in the morning is more beneficial. Dr. Camp explains, “During the day, vitamin C can protect your skin by neutralizing oxygen radicals that develop as a result of exposure to ultraviolet (UV) radiation.”
“In general, it is best to use once daily in the morning after cleansing, prior to moisturizing and sunscreen,” says Dr. Garshick.
Our experts also advise that it is safe to use vitamin C serum daily so long as your skin reacts well to the formula with no irritation or redness.
“Since many forms of vitamin C are unstable, in general, it is best to avoid pairing with exfoliating acids [like AHAs and BHAs], which may impact the pH and decrease stability,” says Dr. Garshick.
You can use retinol and vitamin C in your skincare routine, according to Dr. Garshick and Dr. Camp, but it’s best to use them at different times of the day to avoid skin sensitivity and irritation. Dr. Camp suggests applying “vitamin C products in the morning” to reap the free radical protection during the day, keeping retinol usage to nighttime only.
As great as vitamin C is, the ingredient does have a few hurdles. First, it’s inherently unstable and reactive, easily losing its antioxidant properties when exposed to heat, light, and air. Choose a product packaged in a darkened or opaque bottle with a tight-sealing lid to reduce the likelihood of your vitamin C serum losing its potency over time. Then, ensure you store the vitamin C serum in a cool, dry, dark place (aka not in your bathroom or out on display).
To be effective, Dr. Camp recommends picking a serum with a vitamin C between 10 to 20%. “Vitamin C serums that include stabilizing agents, like vitamin E and ferulic acid, may [also] improve efficacy and shelf life,” he adds.
Our mission at STYLECASTER is to bring style to the people, and we only feature products we think you’ll love as much as we do. Exponent Beauty is a STYLECASTER sponsor, however, all products in this article were independently selected by our editors. Please note that if you purchase something by clicking on a link within this story, we may receive a small commission of the sale.
By providing your information, you agree to our Terms of Use and our Privacy Policy. We use vendors that may also process your information to help provide our services. This site is protected by reCAPTCHA Enterprise and the Google Privacy Policy and Terms of Service apply.